Cerebral Excitement following Mepacrine Therapy

Cerebral Symptoms after Mepacrine *Paper condensed by the editor.

was admitted to the hospital on 13th March, 1945, with high fever. A blood film was examined, and tenue forms of malaria parasites were found. The next day mepacrine one tablet twice daily was prescribed, preceded each time by an alkaline mixture. After taking four tablets of mepacrine, the patient developed peculiar symptoms, staring at the nurses, restlessness, and talking incoherently. She b...

Mepacrine Psychosis

Mepacrine Psychosis

Sib,?It does not seem that a full case has been made against mepacrine by Drs. M. S. H. Mody and Nandi writing about mepacrine psychosis in your issue of May 1947, pages 273-274. It is not said whether their cases were clinical or proven by an examination of the blood-films. It would also be necessary to exclude meningitis by making a lumbar puncture before they can dub mepacrine as the causati...

A Case of Maniacal Excitement Following Large Doses of Atebrin

a state of anxiety. He was uncontrollable, fretful and raving. He assaulted his father, mother and everybody in the house and was unmanageable. He had sudden attacks of panic in which he rushed blindly out into the open street, wandering aimlessly with ceaseless agitation. With much difficulty he was forced into the house by a number of people and locked up in a room. I couldn't examine the pat...

Effect of therapy on cerebral blood flow following aneurysm surgery.

The authors report on a patient with a ruptured anterior communicating aneurysm treated surgically on the day following her subarachnoid hemorrhage (SAH). Repeated measurements of cerebral blood flow (rCBF) were carried out using the inhalational Xenon 133 method. Dramatic acute increases in rCBF occurred, coincident with clinical improvement, following mannitol, CSF drainage and dopamine. Late...